ZnCl2-mediated practical protocol for the synthesis of Amadori ketoses.

Nanishankar, V. Harohally and Sudhanva, M. S. and Sushma, Umesh (2014) ZnCl2-mediated practical protocol for the synthesis of Amadori ketoses. Food Chemistry, 158. pp. 340-344.

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Abstract

An efficient and practical protocol for the synthesis of Amadori ketoses N-(1-deoxy-D-fructose-1-yl) amino acid (amino acid = L-valine (1), L-leucine (2), L-isoleucine (3), L-tryptophan (4), L-phenylalanine (5), L-arginine (6) has been accomplished by employing ZnCl2 as a catalyst. The developed method circumvents protection and deprotection steps as well as tedious ion-exchange and column chromatographic techniques. The accomplished Amadori ketoses showed moderate to weak angiotensin I converting enzyme (ACE) inhibitory activity.

Item Type:	Article
Uncontrolled Keywords:	Amadori rearrangement Zinc ACE
Subjects:	500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 13 Carbohydrate Chemistry
Divisions:	Food Safety Analytical Quality Control Lab
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	16 Jun 2015 10:48
Last Modified:	06 Jul 2015 07:26
URI:	http://ir.cftri.res.in/id/eprint/11826

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