PAF-Acether in AK-5 tumour cells

Gopal, K. Marathe and Krishnakantha, T. P. and Cletus, J.M. D'Souza (1991) PAF-Acether in AK-5 tumour cells. Cell Biology International Reports, 15 (1). pp. 85-90.

PDF Cell Biology International Reports Volume 15 issue 1 1991 [doi 10.1016%2F0309-1651%2891%2990085-W] MARATHE, G; KRISHNAKANTHA, T; DSOUZA, C -- PAF-Acether in AK-5 tumour cells.pdf - Published Version Restricted to Registered users only Download (317kB)

Abstract

PAF-Acether fraction derived from stimulated AK-5 tumour cells, aggregated human platelets. The platelet aggregating ability increased linearly with increasing concentration of the stimulant, calcium ionophore A23187, and reached a maximum at 6 μM in 25 minutes. This factor had biological and chemical properties identical to authentic PAF-acether. Our results demonstrate that, although PAF-acether is produced mainly from pro-inflammatory cells, it appears to be produced even in tumour cells.

Item Type:	Article
Uncontrolled Keywords:	PAF-Acether, AK-5 tumour cells
Subjects:	500 Natural Sciences and Mathematics > 07 Life Sciences > 01 Biology > 01 Cell Biology
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	16 Jul 2018 06:03
Last Modified:	16 Jul 2018 06:03
URI:	http://ir.cftri.res.in/id/eprint/10817

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