Antioxidant activities of tamarind (Tamarindus Indica ) seed coat extracts using in vitro and in vivo models.

Sandesh, V. and Velu, V. and Singh, R. P. (2014) Antioxidant activities of tamarind (Tamarindus Indica ) seed coat extracts using in vitro and in vivo models. Journal of Food Science and Technology, 51 (9). pp. 1965-1973. ISSN 0022-1155

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Abstract

Tamarindus indica seed coat was extracted with methanol, acetone and water and screened for DPPH radical scavenging activities. Methanol extract showed higher activity than other extracts. Treatment of albino rats (Wistar strain) with CCl4 at 1.25 mL/kg of bodyweight decreased superoxide dismutase (55 %), catalase (73 %) and peroxidase (78 %), while lipid peroxidation increased nearly 2.5 fold in liver. Pretreatment of rats with methanol extract of T. Indica seed coat (TSCE) at 50 mg/kg (as tannic acid equivalents) followed by CCl4 treatment, caused restoration of superoxide dismutase, catalase and lipid peroxidation to values close to control while peroxidase was restored to 67 % of the control. Histopathological studies of liver of different groups supported the protective effects of TSCE by restoring the hepatic architecture. These studies could be further extended to exploit its possible application for the preservation of food products as well as a health supplement and neutraceutical.

Item Type:	Article
Uncontrolled Keywords:	Carbon tetrachloride Tamarindus indica Antioxidant Polyphenols Lipid peroxidation Tannic acid
Subjects:	600 Technology > 08 Food technology > 30 Spices/Condiments 600 Technology > 08 Food technology > 32 Antioxidants
Divisions:	Human Resource Development
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	26 Sep 2014 07:39
Last Modified:	03 Jul 2015 07:51
URI:	http://ir.cftri.res.in/id/eprint/11640

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