Recent insights into the molecular regulators and mechanisms of taurine to modulate lipid metabolism: a review.

Arya Devi, K. P. and Asha, Martin (2022) Recent insights into the molecular regulators and mechanisms of taurine to modulate lipid metabolism: a review. Critical Reviews in Food Science and Nutrition, 18. pp. 1-13.

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Abstract

Lipid metabolism disorders such as hypertriglyceridemia and hypercholesterolemia are risk factors for cardiovascular diseases and atherosclerosis that are grave public health issues. Taurine, a sulfur-containing non-essential amino acid exerts a wide range of physiological effects that regulate lipid metabolic disorders. Although the effects of taurine on lipid-lowering have been reported in animals and humans, mechanisms elucidating the lipid-lowering action of taurine remain unclear. A series of molecular regulators associated with lipid metabolism have been identified in the past few decades. These include nuclear receptors, transcription factors, and enzymes that undergo important changes during taurine treatment. In this review, we focus on the role of taurine in lipid metabolism and discuss taurine-related interventions in combating lipid disorders.

Item Type:	Article
Uncontrolled Keywords:	Taurine; hyperlipidemia; lipid metabolism; transcription factors; molecular targets
Subjects:	500 Natural Sciences and Mathematics > 07 Life Sciences > 03 Biochemistry & Molecular Biology > 11 Lipid Biochemistry
Divisions:	Food Safety Analytical Quality Control Lab
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	13 Sep 2022 11:35
Last Modified:	13 Sep 2022 11:35
URI:	http://ir.cftri.res.in/id/eprint/15754

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