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Implication of solvent polarities on browntop millet (Urochloa ramosa) phenolic antioxidants and their ability to protect oxidative DNA damage and inhibit α-amylase and α-glucosidase enzymes.
Raghavakumari, R. Sunagar and Sreerama, Y. N. (2023) Implication of solvent polarities on browntop millet (Urochloa ramosa) phenolic antioxidants and their ability to protect oxidative DNA damage and inhibit α-amylase and α-glucosidase enzymes. Food Chemistry, 411. p. 135474.
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Abstract
Phenolics of browntop millet extracted in solvents with varying polarities [water, methanol, acetone (80%), ethanol (70%)] were comparatively assessed for their phenolic profiles, antioxidant activities, DNA damage protection and enzyme inhibitory properties. Results indicated that acetone (80%) and ethanol (70%) were most effective in extracting millet phenolics than other solvents. Gallic, caffeic and ferulic acids were the major phenolic acids, myricetin and kaempferol were the most abundant flavonoids detected in all the extracts of browntop millet. Phenolics extracted in 80% acetone and 70% ethanol offered noticeable contributions toward several antioxidant mechanisms and prevented the oxidative DNA damage than water and methanol extracts. All the millet extracts exhibited potent inhibition towards α-glucosidase than α-amylase activities. These results suggest that the solvents and their polarities impacted the extraction and bioactivities of millet phenolics and provided useful information for the effective utilization of browntop millet as a functional food ingredient to manage hyperglycemia.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Browntop millet Solvents Phenolic compounds Antioxidant activity DNA damage protection α-Amylase inhibitors α-Glucosidase inhibitors |
| Subjects: | 600 Technology > 08 Food technology > 21 Cereals > 05 Ragi (Finger Millet) 600 Technology > 08 Food technology > 32 Antioxidants |
| Divisions: | Grain Science and Technology |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 16 May 2023 05:29 |
| Last Modified: | 16 May 2023 05:29 |
| URI: | http://ir.cftri.res.in/id/eprint/16357 |
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