A biocompatible nanoformulation of curcumin analogue and curd exosomes targeting EphA2 signalling cascade in head and neck cancer

Kaumudi, Pande and Bettadaiah, B. K. and Anbarasu, Kannan (2024) A biocompatible nanoformulation of curcumin analogue and curd exosomes targeting EphA2 signalling cascade in head and neck cancer. Pande et al. Cancer Nanotechnology, 15 (50). pp. 1-23.

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Abstract

Major therapeutic developments have been made in the preven- tion of head and neck cancer (HNC), and crucial measures have been implemented for the survival of patients. The advent of cancer nano-theranostic as an effective approach targets cancer by allowing drug aggregation at the tumour site, its proper bioaccessibility, and tumour cell death. Curd exosomes are the cellular interactive nan- ovesicles, considered a convenient conveyance medium for cargoes still unexplored. Curcumin analogue alanine is primarily recognised for its superior radical scavenging activity and anti-mutagen properties compared with curcumin.

Item Type:	Article
Uncontrolled Keywords:	Head and neck cancer, Curcumin alanine, Exosomes, EphA2, Mitochondrial dynamics
Subjects:	500 Natural Sciences and Mathematics > 07 Life Sciences > 01 Biology > 01 Cell Biology 600 Technology > 08 Food technology > 30 Spices/Condiments
Divisions:	Plantation Products Spices and Flavour Technology
Depositing User:	Somashekar K S
Date Deposited:	20 Jan 2025 06:42
Last Modified:	20 Jan 2025 06:42
URI:	http://ir.cftri.res.in/id/eprint/18953

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