Effect of beta- & gamma-isomers of hexachlorocyclohexane on some enzyme systems of albino rats.

Srinivasan, K and Radhakrishnamurty, R (1980) Effect of beta- & gamma-isomers of hexachlorocyclohexane on some enzyme systems of albino rats. Indian Journal of Biochemistry and Biophysics, 17 (4). p. 111. ISSN 0301-1208

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Abstract

PESTAB. Rats fed beta- and gamma-BHC (lindane) at 800 ppm for 2 wk showed decreased levels of hepatic mitochondrial DNP/Mg2+/Ca2+-activated ATPases and microsomal Na+,K+-activated ATPases. Reductions in hepatic MDH and LDH activities were also observed, while levels of SDH were elevated. Both isomers caused increases in serum alkaline phosphatase and SGPT activities and decreases in serum acid phosphatase activity. BHC isomer-induced changes in plasma specific enzymes suggested hepatic toxicity. Levels of rat serum albumins tended to decrease and serum globulins increase after feeding with either BHC-isomer. [Presented at the 1979 annual meeting of Indian biochemists.]

Item Type:	Article
Uncontrolled Keywords:	beta isomers hexachlorocyclohexane
Subjects:	500 Natural Sciences and Mathematics > 07 Life Sciences > 03 Biochemistry & Molecular Biology > 08 General Biochemistry
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	03 Feb 2022 08:22
Last Modified:	03 Feb 2022 08:22
URI:	http://ir.cftri.res.in/id/eprint/8618

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