DoseCal: a virtual calculator for dosage conversion between human and different animal species.

Janhavi, P. and Divyashree, S. and Sanjailal, K. P. and Muthukumar, S. P. (2020) DoseCal: a virtual calculator for dosage conversion between human and different animal species. Archives of Physiology and Biochemistry.

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Abstract

Context: The scientists as well as pharmacologists frequently convert the dose of drugs or extracts between human and different animal species. According to the literature, the extrapolation of the dose by simple conversion based only on body weight is not an accurate method. The miscalculation of dosage conversion may result in adverse effects due to overdose or reduced potency due to underdose. Aim: To develop a conversion calculator with factual factor like Km factor. Method: The virtual calculator was developed as a web-based application using hypertext pre-processor programming language. My SQL software was used to store the data related to DoseCal. Results: Based on the Km factor, dose conversion calculator called DoseCal was developed. The DoseCal would provide the dosage for both per kg and actual weight of the animal taken for the experiment. Conclusion: The DoseCal would assist scientists in the dosage conversion easily and accurately between species.

Item Type:	Article
Uncontrolled Keywords:	Dosage conversion; calculator; body surface area; Km factor; animal dose; human dose; dose conversion calculator
Subjects:	000 Computer science, information and general works > 02 Computer Science
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	30 Sep 2020 09:44
Last Modified:	30 Sep 2020 09:44
URI:	http://ir.cftri.res.in/id/eprint/14468

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