Synthesis of hydroxymethylfurfural from cellulose using green processes: A promising biochemical and biofuel feedstock

Inedible, lignocellulosic biomass has been recognized as most promising renewable resource for the
production of high value bio-chemicals. The pretreated biomass or isolated cellulose is a biopolymer of
glucose used as a stating material for the synthesis of 5-hydroxymethylfurfural (HMF). HMF is listed
among the top 10 bio-based chemicals by USA Department of Energy and it acts as feedstock for deriving
a number of commodity products (Bonzell and Petersen, 2010, Green Chem. 12, 539). In present review,
we have systematically summarized the catalytic reaction for the synthesis of HMF from pretreated
biomass/isolated cellulose using green processes. Further, through catalytic approach, HMF is translated
into industrial important chemicals (2,5-diformylfuran, furan-2,5-dicarboxylicacid, 2,5-furandimethanol,
furfuraylalcohol, etc) or high calorific value biofuel (2,5-dimethylfuran, 2,5-dimethyltetrahydrofuran, 2,5-
bis(alkoxymethyl)furans, etc). In the profitable scale of HMF production, levulinic acid (LA) is generated
as a major byproduct. Besides HMF, this review also outlines the catalytic strategy for the conversion of
LA to industrially important chemicals along with the biofuel additives. Finally, the bio-toxicity of syn-
thesized chemicals, which connected into different functional groups have been summarized to meet the
criteria of the green technology for commercialization.