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Clinico-Immunological Analysis of Eggplant (Solanum melongena) Allergy Indicates Preponderance of Allergens in the Peel.
Harish Babu, B. N. and Venkatesh, Y. P. (2009) Clinico-Immunological Analysis of Eggplant (Solanum melongena) Allergy Indicates Preponderance of Allergens in the Peel. World Allergy Organization Journal, 2. pp. 192-200.
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Abstract
Background: Eggplant (Solanum melongena L.) is known to cause food allergy in some Asian countries but detailed studies on eggplant allergy are lacking. Objective: The objective is to investigate sensitization to different parts of eggplant fruit, and detection of the allergens. Methods: Six eggplant-allergic subjects were assessed for sensitization to eggplant (peel/pulp, and raw/cooked) by skin prick test, allergen-specific IgE, and immunoblots. Allergens were analyzed for glycoprotein nature by staining/lectinoblots, and in vitro stability in simulated gastric fluid. Results: All the eggplant-sensitized subjects showed positive skin prick test with peel, pulp, raw, and cooked eggplant extracts; allergen-specific IgE to all these was positive. Raw eggplant contains 5 allergens in the range 36–71 kD. Most allergens are localized in the eggplant peel (9 allergens; 26–71 kD range) than the pulp (3 allergens; 52–71 kD); among these, the 26, 28, 36, and 71 kD allergens seem to be heat-stable. The 43, 45, 64, and 71 kD allergens are detected as glycoproteins; the 26, 64, and 71 kD allergens are stable displaying retention of IgE-binding ability in simulated gastric fluid digestion. Conclusions: Eggplant is a multiallergenic vegetable in the context of presence of allergens in all edible parts of eggplant having preponderance in the peel.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | allergen, eggplant, food allergy, peel, simulated gastric fluid |
| Subjects: | 600 Technology > 08 Food technology > 23 Vegetables |
| Divisions: | Dept. of Biochemistry |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 25 Jul 2011 07:14 |
| Last Modified: | 30 May 2012 07:03 |
| URI: | http://ir.cftri.res.in/id/eprint/10318 |
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