Nandini, Kannan and Manjunatha, J. R. and Bettadaiah, B. K. (2015) Microwave assisted bi-functional activation of β-bromo-tert-alcohols. Journal of Chemical Sciences, 127 (8). pp. 1405-1410.
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Abstract
Microwave-assisted dehydration-oxidation of β-bromo-tert-alcohols to afford 2,3-unsaturated
ketones in good yield is reported. The reaction of substrates with DMSO in 1:1 ratio (w/v) is promoted by
ZnS in a solvent-free condition. A concurrent bi-functional activation of trans-vicinal bromo- and hydroxyl
groups with ZnS is elucidated. This is a new observation under microwave and applies to β-bromo-tert-alcohols
derived from 1,4-disubstitued-1-cyclohexenes. It is very useful in the synthesis of 2,3-unsaturated ketones
derived from monoterpenes which are valuable flavour compounds.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | β-Bromo-tert-alcohols; microwave; bi-functional activation; ZnS; flavour compounds. |
| Subjects: | 500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 24 Organic Chemistry 600 Technology > 08 Food technology > 30 Spices/Condiments |
| Divisions: | Plantation Products Spices and Flavour Technology |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 11 Dec 2015 08:21 |
| Last Modified: | 11 Dec 2015 08:21 |
| URI: | http://ir.cftri.res.in/id/eprint/12030 |
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