Kinetics and thermodynamics in downstream processing of medicinal fungi C. sinensis CS1197.

Shashidhar, M. G. and Giridhar, P. and Manohar, B. (2017) Kinetics and thermodynamics in downstream processing of medicinal fungi C. sinensis CS1197. Biochemical Engineering Journal, 121. pp. 88-93. ISSN 1369-703X

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Abstract

The kinetics of solid-liquid extraction of bioactive adenosine and cordycepin from the mycelia of C. sinensis CS1197 was studied. Hot water extraction was carried out at temperature 70, 80 and 90 ◦C and pH 3, 4 and 5 and mechanism of extraction was studied by applying Fick’s diffusion and empirical models. Akaike information criterion (AIC) was employed for selection of the best model among candidate models. Based on AIC, the parabolic diffusion model was found to be the best among competitive models with high R2 value. Diffusion coefficient for adenosine and cordycepin extraction were 1.06 10−12–2.13 10−12 and 1.06 10−12–2.85 10−12m2 s−1 respectively. Thermodynamic analysis of the process revealed that extraction of adenosine and cordycepin is feasible, endothermic and spontaneous at pH 4 and temperature 70 ◦C.

Item Type:	Article
Uncontrolled Keywords:	Filamentous fungi Downstream processing Diffusion Modeling Akaike information criterion Thermodynamics
Subjects:	500 Natural Sciences and Mathematics > 08 Botanical sciences > 01 Botany > 03 Fungi 600 Technology > 08 Food technology > 05 Processing and Engineering
Divisions:	Food Engineering Plant Cell Biotechnology
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	11 Jan 2018 04:17
Last Modified:	11 Jan 2018 04:17
URI:	http://ir.cftri.res.in/id/eprint/13278

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