Interrelationships between folic acid and vitamin B12 in Escherichia coli methionine auxotroph.

Netrawali, M. S. and Pradhan, D. S. and Doctor, D. M. and Sreenivasan, A. (1964) Interrelationships between folic acid and vitamin B12 in Escherichia coli methionine auxotroph. Bulletin of National Institute of Science in India, 25. pp. 113-118.

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Abstract

Cells of E.rcherichia coli vitamin B,,/methionine auxotroph have been shown to possess an ability to convert tetrahydrofolic acid to N'-formyltetrahydrofolic acid. Optimum conditions for this conversion have been worked out. It was shown that serine is a better one-carbon donor than formate. Vitamin BI' suppresses conversion of tetrahydrofolic acid to N'-formyltetrahydrofolic acid when serine is used as one-carbon donor and stimulates it when the one-carbon donor is formate. Vitamin B" antagonists do not have any effect on tbis conversion.

Item Type:	Article
Uncontrolled Keywords:	folic acid, vitamin B12, methionine auxotroph, enzymatic biosynthesis, Escherichia coli
Subjects:	600 Technology > 01 Medical sciences > 12 Metabolism 600 Technology > 08 Food technology > 16 Nutritive value > 04 Vitamins
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	02 Aug 2013 09:01
Last Modified:	02 Aug 2013 09:01
URI:	http://ir.cftri.res.in/id/eprint/4495

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