Effect of dietary fiber and butyric acid on lysosomal enzyme activities in streptozotocin-induced diabetic rats.

Puneeth Kumar, A. and Shetty, A. K. and Salimath, P. V. (2006) Effect of dietary fiber and butyric acid on lysosomal enzyme activities in streptozotocin-induced diabetic rats. European Food Research and Technology, 222 (5-6). 692-696 ; 41 ref..

PDF Eur_Food_Res_Technol_(2006)_222_692–696.pdf Restricted to Registered users only Download (215kB)

Abstract

The effect of dietary fibre and butyric acid on lysosomal enzyme activities in different tissues of streptozotocin-induced diabetic rats was studied by analysing the specific activities of N-acetyl-beta-D-glucosaminidase, beta-D-glucuronidase, beta-D-galactosidase and acid phosphatase in various tissues. An alteration in the activities of these lysosomal enzymes in different tissues was observed in streptozotocin-induced diabetic rats. Dietary fibre and butyric acid supplementation at 500 mg/kg body wt./day was found to be effective in modulating the altered glycosidase activity in liver, spleen, heart, lungs, testis and brain during diabetes. Results also indicated that butyric acid along with dietary fibre is involved in minimizing oxidative stress-induced tissue damage, thereby regulating the altered enzyme activities in different tissues during diabetes.

Item Type:	Article
Uncontrolled Keywords:	BUTYRIC-ACID; DISEASES-; FIBRE-; HUMAN-PHYSIOLOGY; ANIMAL-MODELS; DIABETES-; DIETARY-FIBRE; PHYSIOLOGICAL-EFFECTS
Subjects:	600 Technology > 01 Medical sciences > 04 Diabetes Mellitus 600 Technology > 08 Food technology > 18 Processed foods > 01 Dietary Fiber
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	26 Jun 2009 06:16
Last Modified:	28 Dec 2011 09:58
URI:	http://ir.cftri.res.in/id/eprint/7512

Actions (login required)

View Item