Studies on skin and urinary mucopolysaccharides in malnourished/vitamin A deficient children.

Latif, K. A. and Amla, I. and Rao, P. B. R. (1982) Studies on skin and urinary mucopolysaccharides in malnourished/vitamin A deficient children. Clinica Chimica Acta, 122 (3). 317-325; 21 ref..

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Abstract

In protein-energy malnourished children, with or without associated vitamin A deficiency, skin content of acid mucopolysaccharides (MPS) and excretion of MPS and amino sugars in urine were studied. MPS content of skin in both malnourished groups was increased 3- to 6-fold. That increase was almost entirely in the nonsulphated component. In normal skin, nonsulphated MPS accounted for 68% of the MPS content, whereas in the malnourished group with vitamin A deficiency it was 93%. Excretion of MPS in urine (24 h) was significantly decreased by 50 to 70% in the malnourished groups. That returned to normal in the malnourished/vitamin A deficient group when vitamin A was given by injection. Excretion of amino sugars in urine (24 h) of the malnourished groups was also decreased by 50 to 70%. In normal children 55% of the total amino sugars was dialysable, whereas in the malnourished it was increased to 60%. The excretion of protein-bound and dialysable amino sugars was increased to normal only in the group given supplements of vitamin A in addition to protein and energy.

Item Type:	Article
Uncontrolled Keywords:	children-; malnutrition-; mucopolysaccharides-; skin-; urine-; vitamin-A-deficiency
Subjects:	600 Technology > 01 Medical sciences > 11 Malnutrition
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	23 Feb 2018 08:49
Last Modified:	23 Feb 2018 08:49
URI:	http://ir.cftri.res.in/id/eprint/8570

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