Antibacterial Properties of Secoisolariciresinol Diglucoside Isolated from Indian Flaxseed Cultivars.

Secoisolariciresinol diglucoside (SDG) is an
important lignan found in flaxseed and is an
emerging source in the functional food area. In
the present study, antibacterial properties of SDG
extracts from hull, endosperm and flour fractions
of Indian flaxseed (Linum usitatissimum)
varieties (LVF-01 and GVF-03) were evaluated.
The SDG extracts were tested against the six
bacterial species Pseudomonas aeruginosa,
Staphylococcus aureus, Bacillus subtilis,
Agrobacterium tumefaciens, Bacillus cereus,
and Escherichia coli. The maximum SDG and
phenolic contents were found to be 16.9 and 12.5
mg/g and 3.18 and 2.70 mg/g in hull fractions of
LVF-01 and GVF-03 respectively, when
compared to flour and endosperm fractions.
Among the fractions, the hull fraction of LVF-01
showed maximum activity 31.5 mm at MIC 100
ppm against E. coli, while minimum inhibitory
activity was 3.1 mm with MIC at 300 ppm against
B. subtilis. Similarly, in the case of GVF-03,
maximum activity (31.9 with MIC 150 ppm) of
the hull fraction, whereas, its minimum inhibitory
activity was (2.3 mm, with MIC 350 ppm) against
B. subtilis, when compared to endosperm and
flour ractions.