Santosh Kumar, S. C. and Negi, P. S. and Manjunatha, J. R. and Bettadaiah, B. K. (2017) Synthesis, antibacterial and antimutagenic activity of zerumbonebicarbonyl analogues. Food Chemistry, 221. pp. 576-581.
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Abstract
Synthesis of new zerumbone-bicarbonyl analogues by SeO2 oxidation is reported. Selective oxidation of
methyl at C-13 to an aldehyde and a ketone with exo-cyclic double bond between C-13 and C-6 in zerumbone
has been recognized. Both these compounds have an additional conjugated-carbonyl-functionality.
They exhibited significantly higher antimutagenic activity than zerumbone against Salmonella tester
strains. They are more active against Gram positive bacteria than Gram negative bacteria; however
zerumbone showed highest activity against E. coli, whereas its derivatives were least effective against
E. coli.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Selenium dioxide Zerumbal Zerumbenone Antibacterial activity Anti-mutagenic activity |
| Subjects: | 600 Technology > 08 Food technology > 30 Spices/Condiments |
| Divisions: | Fruit and Vegetable Technology Plantation Products Spices and Flavour Technology |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 28 Dec 2016 10:23 |
| Last Modified: | 28 Dec 2016 10:23 |
| URI: | http://ir.cftri.res.in/id/eprint/12599 |
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