Sindhuja, H. N. (2016) Studies on the Role of Dietary Galectin- Inhibitor on Galectin and Galectin Binding Protein Mediated Metastasis. Doctoral thesis, Central Food Technological Research Institute.
![[thumbnail of Sindhuja.pdf]](http://ir.cftri.res.in/style/images/fileicons/other.png "Sindhuja.pdf")
PDF
Sindhuja.pdf - Submitted Version
Restricted to Repository staff only
Download (15MB)
Abstract
Metastasis is a crucial step in cancer pathogenicity and adds severity to the
disease mainly because of the entry of cancer cell into a highly manipulative
stage. Several studies including studies from our laboratory have indicated
that galectin-3 plays a key role in metastasis. Galectin-3 binding protein
(G3BP) is reported as a ligand for galectin-3. G3BP is a heavily Nglycosylated
protein with a molecular mass of 90 kDa and it appears to
mediate cell-cell adhesion via bridging galectin-3 molecules on adjacent
tumor cells in a carbohydrate-dependent manner.
| Item Type: | Thesis (Doctoral) |
|---|---|
| Uncontrolled Keywords: | galectin-3 G3BP mediated metastasis |
| Subjects: | 500 Natural Sciences and Mathematics > 07 Life Sciences > 03 Biochemistry & Molecular Biology > 16 Protein Biochemistry |
| Divisions: | Dept. of Biochemistry |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 13 Jul 2017 08:58 |
| Last Modified: | 13 Jul 2017 08:58 |
| URI: | http://ir.cftri.res.in/id/eprint/12821 |
Actions (login required)
- View Item