Concentrates from tender coconut water and coconut testa beneficially modulates tissue lipid profiles in high-fat fed rats.

The present study involved feeding of tender
coconut water concentrate (TCW) and testa phenolic concentrate
(PHE) to high fat fed animals. Analysis of serum
showed increased HDL-C in concentrates treated group and
therefore higher protection against atherogenesis compared to
high fat fed group. Lesser fecal fat content and higher level of
liver cholesterol were observed in high fat fed group, treatments
with TCW and PHE ameliorated significantly. Fat
content in the organs (liver, heart, kidney and adipose) of
HFD group was high. Furthermore, certain fatty acids
observed in the tissues were 14:0, 16:0, 18:0, 18:1, 18:2, 20:0,
20:3 and 20:4, among which 14:0, 16:0 & 18:0 are the major
saturated fatty acids that increased significantly in high fat fed
group when compared with starch fed group and ameliorated
with TCW and PHE dose dependently. These results clearly
indicate both the concentrates (TCW and PHE) restrict excess
accumulation of lipids and altered composition of fatty acids
in tissues as well as serum which are the risk factors for
development of insulin resistance, hyperlipidemia, dyslipidemia
etc., related to obesity.