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Rhus chinensis Mill.: A medicinal plant with promising inhibition of calcium oxalate crystallization, an in-vitro study.
Memthoi Devi, H. and Iboyaima Singh, N. (2021) Rhus chinensis Mill.: A medicinal plant with promising inhibition of calcium oxalate crystallization, an in-vitro study. Journal of Herbal Medicine.
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Abstract
The fruit of Rhus chinensis Mill. is traditionally used for the treatment of kidney diseases and urinary stones. The present work investigated the effectiveness of the extract obtained from the R. chinensis fruit pulp (RCFP) (water extract) on the inhibition of calcium oxalate (CaOx) crystallization in-vitro, at different concentrations (1-10 mg/ml). The rates of nucleation and aggregation were evaluated by comparing the slope of turbidity in the presence of the fruit extract with that obtained in the control. The results of the samples were compared with a parallel study conducted with standards like Citric acid (CA) and Malic acid (MA), Cystonea marketed polyherbal combination (CYS), under identical concentrations. The densities of the formed crystals were observed under a light microscope. RCFP (water extract) significantly inhibited the slope of nucleation and aggregation of CaOx crystallization, and decreased the crystal density. The standards- CA, MA and CYS also exhibited similar effects. The study reveals that the organic acid in RCFP (water extract) was found effective in the prevention of the experimentally induced urinary stones and thus substantiating the traditional claim. Hence, the fruit of R. chinensis has a beneficial inhibitory effect on in-vitro crystallization of CaOx crystals.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Rhus chinensis Mill.; Calcium oxalate; Anti-crystallization; Nucleation; Aggregation |
| Subjects: | 600 Technology > 03 Agriculture > 04 Medicinal Plants |
| Divisions: | Fruit and Vegetable Technology |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 26 Nov 2021 05:15 |
| Last Modified: | 26 Nov 2021 05:15 |
| URI: | http://ir.cftri.res.in/id/eprint/15097 |
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