Lack of adverse influence of black pepper, its oleoresin and piperine in the weanling rat.

Black pepper, its oleoresin or its active principle piperine fed to ruts
at doses 5 to 20 times normal human intake did not cause any adverse
effect on: ( I ) growth, food eficiency ratio and organ weights; (2) RBC,
WBC and differential counts; (3) the levels of blood constituents like
hemoglobin, total serum proteins, albumin, globulin, sugar and cholesterol;
(4) the levels of serum aminotransferases and phosphatases and (5) fat
and nitrogen balance.