Metabolism of curcumin - studies with [-3H]curcumin.

Ravindranath, V. and Chandrasekhara, N. (1982) Metabolism of curcumin - studies with [-3H]curcumin. Toxicology, 22 (4). 337-344, 12 ref..

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Abstract

Radioactivity was detectable in blood, liver and kidney of rats following dosage with 400, 80 or 10 mg of [-3H]curcumin, the major pigment of turmeric (Curcuma longa). The major route of elimination of the label was the faeces: urinary excretion of the label was very low regardless of the dose. At the lower doses of 80 and 10 mg, most of the label was excreted within 72 h, while with 400 mg, considerable amounts of the label were present in the tissues 12 days after dosage. The % of curcumin absorbed (60-66% of the dose given) remained constant regardless of the dose administered.

Item Type:	Article
Uncontrolled Keywords:	SORPTION-; curcumin, rats absorption of; PIGMENTS-
Subjects:	600 Technology > 08 Food technology > 30 Spices/Condiments 600 Technology > 01 Medical sciences > 17 Toxicology
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	17 Jun 2011 09:45
Last Modified:	28 Dec 2011 09:55
URI:	http://ir.cftri.res.in/id/eprint/6737

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