Study on the levels of trace elements in mild and severe psoriasis

Basavaraj, K. H. and Darshan, M. S. and Shanmugavelu, P. and Rashmi, R. and Mhatre, A. Yuti and Dhanabal, S. P. and Rao, K. S. J. (2009) Study on the levels of trace elements in mild and severe psoriasis. Clinica Chimica Acta, 405 (1-2). pp. 66-70. ISSN 0009-8981

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Abstract

Background Psoriasis is a chronic, recurrent skin disorder characterized histologically by cutaneous inflammation, increased epidermal proliferation, hyperkeratosis, angiogenesis, abnormal keratinization, shortened maturation time and parakeratosis. Data on the involvement of trace elements in the pathogenesis of psoriasis is limited.Methods The elements namely Na, K, Ca, P, S, Mg, Cu, Zn, and Fe were analyzed in the serum samples of mild and severe psoriasis patients with a control group using inductively coupled plasma-atomic emission spectroscopy (ICP-AES). Patients were assessed as per standard clinical diagnostic criteria and classified into mild and severe psoriasis groups using Psoriasis Area Severity Index (PASI) score.Results In mild psoriasis, the levels of K, P, Cu, and Mg were increased significantly (p

Item Type:	Article
Uncontrolled Keywords:	Serum Trace elements Psoriasis Metal homeostasis Oxidative stress
Subjects:	600 Technology > 01 Medical sciences > 17 Toxicology
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	23 Feb 2018 08:39
Last Modified:	23 Feb 2018 08:39
URI:	http://ir.cftri.res.in/id/eprint/9031

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