Ultrasound-Assisted Nucleophilic Substitution Reaction of t-Alkyl Halides with Zinc and Titanium Thiocyanate

Bettadaiah, B. K. and Gurudutt, K. N. and Srinivas, P. (2003) Ultrasound-Assisted Nucleophilic Substitution Reaction of t-Alkyl Halides with Zinc and Titanium Thiocyanate. Synthetic Communications, 33 (13). pp. 2293-2299.

PDF Synthetic_Communications,_2003,_33(13)_2293.pdf Restricted to Registered users only Download (87kB)

Abstract

Ultrasoundpromotes nucleophilic substitution of t-alkyl halides with ambident thiocyanate nucleophile, in the form of its zinc or titanium thiocyanate, under mild conditions to afford the corresponding thiocyanates selectively, in goodto excellent yields. This improved synthetic methodology affords a facile access to tertiary thiols via the corresponding thiocyanate intermediates.

Item Type:	Article
Uncontrolled Keywords:	Ultrasound; Nucleophilic substitution; t-Alkyl halides; Zinc; Titanium; Thiocyanates; Isothiocyanates; Thiols.
Subjects:	500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 04 Analytical Chemistry 600 Technology > 08 Food technology > 15 Flavour/Fragrance/Perfumes
Divisions:	Plantation Products Spices and Flavour Technology Food Safety Analytical Quality Control Lab
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	19 Jun 2009 06:37
Last Modified:	19 Jun 2009 06:37
URI:	http://ir.cftri.res.in/id/eprint/9104

Actions (login required)

View Item