Saeedeh, Arabshahi Delouee and Mehran, Aalami and Asna, Urooj and Krishnakantha, T. P. (2010) Moringa oleifera Leaves as an Inhibitor of Human Platelet Aggregation. Pharmaceutical Biology, 47 (8). pp. 734-739.
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Abstract
Moringa oleifera L. (Moringaceae) leaves were examined for their effect on human platelet aggregation in
vitro. The aqueous extract of Moringa oleifera leaves significantly (p ≤0.05) inhibited platelet aggregation
induced by agonists such as adenosine diphosphate, collagen, and epinephrine. The degree of inhibitory
activity varied depending on the agonist used, concentration of extract and duration of incubating the
extract with platelets. Heat treatment reduced the inhibitory activity of extract against platelet aggregation.
In addition, the extracts significantly (p ≤0.05) decreased the amount of malonaldehyde formed in
agonist challenged platelets. This study is the first report on the effect of aqueous extract of Moringa oleifera
leaves against human platelet aggregation. Overall, Moringa oleifera leaves have potential to protect
platelets against aggregation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Moringa oleifera; inhibitory activity; platelet aggregation |
| Subjects: | 600 Technology > 08 Food technology > 23 Vegetables 600 Technology > 01 Medical sciences > 12 Metabolism |
| Divisions: | Dept. of Biochemistry |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 28 Sep 2010 10:40 |
| Last Modified: | 01 Jul 2015 11:07 |
| URI: | http://ir.cftri.res.in/id/eprint/9740 |
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