Capsaicin: A Promising Multifaceted Drug from Capsicum spp

Prasad, B. C. N. and Richa, Shrivastava and Ravishankar, G. A. (2006) Capsaicin: A Promising Multifaceted Drug from Capsicum spp. Evidence Based Integrative Medicine, 2 (3). pp. 142-166.

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Abstract

Capsaicin, the pungency-impat1ing alkaloid, is found only in the Capsicum genus. Capsaicin biosynthesis involves the phenyl propanoid and valine pathways and a final condensation step to involve ~'anillylamjne and 8-methyl nonenok acid catalysed by capsaicin synthase. In recent times, capsaicin has been one of the most highly exploited biomolecules because of its versatility in application. So far, researchers have reported capsaicin as an antioxidant. antiarthritic. gastroprotcctive agent, anticancer (also procancer) agent and an analgesic. This review is a compilation of reports on the biosynthesis of capsaicin in Capsicum spp .. the exploitation of capsaicin in pharmacy and the molecular mechanisms involved in capsaicin receptors.

Item Type:	Article
Uncontrolled Keywords:	capsaicin, capsicum, alkaloid
Subjects:	500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 02 Alkaloids Chemistry 600 Technology > 08 Food technology > 30 Spices/Condiments
Divisions:	Plant Cell Biotechnology
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	24 Nov 2017 10:40
Last Modified:	24 Nov 2017 10:40
URI:	http://ir.cftri.res.in/id/eprint/13174

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