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Physico-chemical characteristics and fibril-forming capacity of carp swim bladder collagens and exploration of their potential bioactive peptides by in silico approaches.
Gaurav Kumar, Pal and Suresh, P. V. (2017) Physico-chemical characteristics and fibril-forming capacity of carp swim bladder collagens and exploration of their potential bioactive peptides by in silico approaches. International Journal of Biological Macromolecules, 101. pp. 304-313.
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Abstract
This study explores the sustainable valorization of carp swim bladder by-products. The high-value molecule collagens were successfully extracted from carp swim bladder with a yield of ∼60% (dry weight basis) and characterized by sodium dodecyl sulfate polyacrylamide gel electrophoresis, UV-spectrum and Fourier transform infrared spectroscopy. The extracted collagens showed the fibril-forming ability and high denaturation temperature (38-39°C). Furthermore, the extracted collagens subjected to preparing bioactive collagen hydrolysates with potential antioxidant activities. In vitro and In silico approaches (PepDraw, BIOPEP, PeptideRanker, Pepcalc and ToxinPred) were employed to evaluate the potential of carp collagens as a potential source of bioactive peptides. Furthermore, primary structure, biological potential, physicochemical, sensory and toxicity characteristics of the theoretically release antioxidative collagen peptides were predicted. Overall, the present study highlights the carp collagens hydrolysate could be a promising precursor of bioactive peptides for developing functional food or nutraceutical products.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Antioxidative collagen peptides; Carp swim bladder collagen; Collagen hydrolysates; In silico analysis; Valorization |
| Subjects: | 500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 25 Peptide Chemistry 600 Technology > 08 Food technology > 28 Meat, Fish & Poultry > Fish |
| Divisions: | Meat Fish and Poultry Technology |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 11 Jan 2018 06:18 |
| Last Modified: | 11 Jan 2018 06:18 |
| URI: | http://ir.cftri.res.in/id/eprint/13283 |
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