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Lipase catalyzed esterification of α-terpineol with various organic acids: application of the Plackett–Burman design

Rao, Pramila and Divakar, S. (2001) Lipase catalyzed esterification of α-terpineol with various organic acids: application of the Plackett–Burman design. Process Biochemistry, 36. pp. 1125-1128.

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Abstract

The orthogonal Plackett–Burman statistical experimental design was employed to study the efficacy of the lipase-mediated esterification of α-terpineol with a wide variety of organic acids. A two level design used to study the effect of eleven carboxylic acids of carbon chain length C2 to C18 identified all the acids to be significant, implying that corresponding esters of α-terpineol were produced in substantial amounts, 18.7–41.1%, on using lipase as catalyst. The Plackett–Burman design, not attempted in lipase catalysis before, is a reliable method to short-list the best organic acid from a wide range or understand the extent of esterification possible under a given set of conditions in a very small number of experiments.

Item Type: Article
Uncontrolled Keywords: Plackett–Burman design; α-Terpineol; Chirazyme
Subjects: 600 Technology > 05 Chemical engineering > 01 Biotechnology and Bioengineering
500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 16 Enzyme Chemistry
Divisions: Fermentation Technology and Bioengineering
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 03 Oct 2007 11:10
Last Modified: 28 Dec 2011 09:30
URI: http://ir.cftri.res.in/id/eprint/1463

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