Production Of Novel Lipase Inhibitor From Streptomyces Sp

Kilaru, Naveen Babu (2005) Production Of Novel Lipase Inhibitor From Streptomyces Sp. PhD thesis, University of Mysore.

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Abstract

In the area of microbial metabolites, a new horizon was opened about 3 decades ago when the systematic search for small molecular enzyme inhibitors and other bioactive metabolites from fermentation broths started. Although a number of investigations have been carried out on the isolation of pancreatic lipase inhibitors from synthetic, plant and microbial sources, only a few compounds were reported from actinomycetes. Moreover, there are only a few systematic studies on the screening, isolation, characterization and media optimization for the production of pancreatic lipase inhibitors. In spite of the development of synthetic compounds for pancreatic lipase inhibition, only a few compounds have gone to the marketing stage. Further, there is a need for the isolation of new and novel metabolites from the available natural sources, thus leading to the development of powerful inhibitors. The present work is an attempt to screen, isolate and characterize pancreatic lipase inhibitor from actinomycetes.

Item Type:	Thesis (PhD)
Uncontrolled Keywords:	Microorganisms Actinomycetes Lipases Lipase inhibitors Streptomyces sp
Subjects:	500 Natural Sciences and Mathematics > 07 Life Sciences > 04 Microbiology 500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 16 Enzyme Chemistry
Divisions:	Fermentation Technology and Bioengineering
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	03 Dec 2007 06:40
Last Modified:	28 Dec 2011 09:31
URI:	http://ir.cftri.res.in/id/eprint/1528

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