Lipase catalyzed synthesis of L-alanyl, L-leucyl and L-phenylalanyl esters of D-glucose using unprotected amino acids.

Vijayakumar, G. R. and Lohith, K. and Somashekar, B. R. and Divakar, S. (2004) Lipase catalyzed synthesis of L-alanyl, L-leucyl and L-phenylalanyl esters of D-glucose using unprotected amino acids. Biotechnology letters, 26 (17). pp. 1323-1328. ISSN 0141-5492

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Abstract

Enzymatic synthesis of l-alanyl, l-leucyl and l-phenylalanyl esters of D-glucose was carried out in a non-polar solvent using lipases from Rhizomucor miehei and porcine pancreas. The unprotected amino acids at millimolar concentrations were used in presence of 10 to 50% (w/w) glucose of the lipases to give ester yields up to >99%. The reaction mixture on analysis by 2-D NMR showed that the product is a mixture of 6-O-, 3-O- and 2-O-monoesters and 2,6-di-O- and 3,6- di-O-esters.

Item Type:	Article
Uncontrolled Keywords:	L-alanyl-D-glucose; Esterification; L-leucyl-D-glucose; L-phenylalanyl-D-glucose
Subjects:	600 Technology > 08 Food technology > 11 Food Biochemistry
Divisions:	Fermentation Technology and Bioengineering
Depositing User:	Users 197 not found.
Date Deposited:	03 Jun 2011 10:32
Last Modified:	16 May 2012 08:46
URI:	http://ir.cftri.res.in/id/eprint/2010

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