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A study of plasma and liver lipid profile of rats fed palm oil or safflower oil along with cholesterol.

Purushothama, S. and Narasimhamurthy, K. and Raina, P. L. and Hariharan, K. (1994) A study of plasma and liver lipid profile of rats fed palm oil or safflower oil along with cholesterol. Nutrition Research, 14 (2). pp. 255-269.

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Male weanling Wistar rats were fed synthetic diets containing 20% safflower oil or 20% palm oil along with 0.3% cholesterol for a period of 6 weeks. The control groups were fed with the same 20% oil diets without cholesterol. The dietary treatment did not alter the food intake or the growth rate as compared to controls. The plasma cholesterol of the cholesterol supplemented groups had in general the expected higher level, and cholesterol associated with HDL, LDL and VLDL fractions was more in the palm oil group. Triglycerides were higher in palm oil group and there was no significant difference with respect to phospholipids. Analysis of liver cholesterol indicated more of esterified cholesterol with palm oil group than with the safflower oil group. Analysis of liver and plasma fatty acids generally reflected the type of oil intake as evidenced by the increased level of palmitic (16:0), oleic (18:1) and linoleic acids (18:2), besides a higher concentration of arachidonic acid (20:4) in safflower oil fed groups. The fatty acid composition of the control and cholesterol supplemented roups demonstrated a similar P/S ratio, 16:0/18:1 ratio andg18:i/ 18:2 ratio as that of the diet provided to these animals and indicated the storage of linoleic acid (18:2) in the liver. Thus, our studies indicate the type of fat has a favourable influence on the cholesterol of the plasma and the liver, and indicate that palm oil has a favourable effect on the cholesterol metabolism similar to unsaturated safflower oil.

Item Type: Article
Uncontrolled Keywords: Palm oil, Safflower oil, Hypercholesteremia, Plasma lipids, Liver lipids, Fatty acids Growth
Subjects: 600 Technology > 08 Food technology > 19 Lipids-oils/fats
600 Technology > 01 Medical sciences > 05 Dietetics
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 15 Jun 2011 07:11
Last Modified: 18 Nov 2016 11:08
URI: http://ir.cftri.res.in/id/eprint/2607

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