Comparative toxicities of shoxin to different test animals.

Krishnakumari, M. K. (1964) Comparative toxicities of shoxin to different test animals. Proceedings of the symposium on Pesticides, Mysore. pp. 187-189.

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Abstract

Recently a specific carboximide tmder the trade name Shoxin has been synthesized in U.S.A. and claimed to be toxic only to lWltus rattus. Acute toxicity experiment, of the chemical 'ShQxin' (5-(a-hydroyey-a-Z-pyridylbenzyl)-7a- Z-pyridylbenzylidene-5-norbomene-Z-, 3.dicarboximide), to various animal species were conducted. This chemical did nOi have any effect on the animals like Indian gerbil, guineapigs, rahbits, pigeons and cockerels when fed at 600 mg.{kg. body weight and invertebrates like earthworms and insects. During the experimental period of fifteen days all the animals were normal and did not show any toxic symptom. Shoxin killed Rauu> raltus within two hours at 64mg./ kg. body weight. Albino rats (R. Iwrvegicus) were more susceptible than Rallus raltus and some albino rats died instantaneously at 6 mg,/kg. body weight level. Some anticoagulant and vasodilator dnlgs when tested did no t alter the toxicity of Shoxin.

Item Type:	Article
Uncontrolled Keywords:	carboximide, Shoxin, Acute toxicity
Subjects:	600 Technology > 01 Medical sciences > 17 Toxicology
Divisions:	Food Protectants and Infestation Control
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	19 Jun 2014 07:14
Last Modified:	19 Jun 2014 07:14
URI:	http://ir.cftri.res.in/id/eprint/3573

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