Effect of chemical modification on the binding of gossypol by gossypin (11S protein) and congossypin (7S protein) of cottonseed.

Mohan Reddy, I. and Narasinga Rao, M. S. (1987) Effect of chemical modification on the binding of gossypol by gossypin (11S protein) and congossypin (7S protein) of cottonseed. Journal of Biosciences, 12 (3). pp. 203-209.

PDF J. Biosci., Vol. 12, Number 3, September 1987, pp. 203-209.pdf - Published Version Restricted to Registered users only Download (661kB) | Request a copy

Abstract

Binding of gossypol by gossypin and congossypin and their succinylated and sulfhydryl group-blocked derivatives has been measured. The binding by gossypin and congossypin is characterized by weak interaction. Succinylation of gossypin decreases the binding affinity whereas that of congossypin increases it. Blocking of sulfhydryl groups of both the proteins does not significantly affect gossypol binding, Succinylation dissociates gossypin and causes conformational changes whereas it does not dissociate congossypin but causes conformational changes. Sulfhydryl group blocking does not dissociate gossypin or congossypin, nor does it cause any conformational changes.

Item Type:	Article
Uncontrolled Keywords:	Gossypol; gossypin; congossypin; binding; chemical modification; cottonseed
Subjects:	600 Technology > 08 Food technology > 16 Nutritive value > 03 Proteins 600 Technology > 08 Food technology > 19 Lipids-oils/fats > 03 Cotton seed
Divisions:	Protein Chemistry and Technology
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	14 Mar 2018 04:11
Last Modified:	14 Mar 2018 04:11
URI:	http://ir.cftri.res.in/id/eprint/3853

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