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Inclusion of cellulose in calorie-restricted diets. Effect on body composition, nitrogen balance, and cholesterol level in obese rats.

Sundaravalli, O. E. and Shurpalekar, K. S. and Rao, M. N. (1973) Inclusion of cellulose in calorie-restricted diets. Effect on body composition, nitrogen balance, and cholesterol level in obese rats. Journal of the American Dietetic Association, 62 (1). pp. 41-44.

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Abstract

Restricted amounts of an experimental diet, 6 g/day, containing 25% casein without or with 2 g cellulose/day in a finely divided form were given for 6 weeks to rats made obese by having had to appetite a diet with 60% hydrogenated fat. Decreases in body fat alone accounted for 67 to 88% of the loss in bodyweight. In spite of low energy intake, the rats maintained a slight positive N balance. There was a significant fall in serum and liver cholesterol and lipids with weight loss without and with cellulose in the diet. The total serum lipids of rats given cellulose supplements were significantly less than those of rats not given it. Supplements of microcrystalline cellulose given with a restricted amount of the experimental diet did not exert deleterious effects on N balance. The study has demonstrated the utility of inclusion of bulking agents, such as microcrystalline cellulose, in the diets of experimental obese rats at 25% of total dietary intake. Whether inclusion of bulking agents has similar effects in obese human subjects is open to conjecture and requires further research.

Item Type: Article
Uncontrolled Keywords: underfeeding-; treatment-; obesity-; cellulose-; body-composition; nitrogen-; retention-; cholesterol-
Subjects: 600 Technology > 01 Medical sciences > 13 Nutrition-Human
600 Technology > 08 Food technology > 18 Processed foods > 01 Dietary Fiber
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 17 Feb 2022 06:03
Last Modified: 17 Feb 2022 06:03
URI: http://ir.cftri.res.in/id/eprint/8604

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