Vijendra Kumar, N. and Srinivas, P. and Bettadaiah, B. K. (2012) New scalable and eco-friendly synthesis of gingerols. Tetrahedron Letters, 53. pp. 2993-2995. ISSN 0040-4039
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Abstract
Synthesis of 6-gingerol and its congeners 7- and 9-gingerols has been achieved from eugenol by a new
scalable and eco-friendly protocol. The key steps are functionalization of eugenol to the nitro compound
and its reaction under optimized condition with terminal alkenes to afford intermediate isoxazolines. The
latter on catalytic hydrogenation in presence of Raney nickel afford corresponding gingerols in good
yields.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 6-Gingerol, Eugenol, Hydroboration, Eugenyl iodide Isoxazolines, Olefins, Reduction |
| Subjects: | 600 Technology > 08 Food technology > 01 Analysis 600 Technology > 08 Food technology > 30 Spices/Condiments |
| Divisions: | Plantation Products Spices and Flavour Technology |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 22 May 2012 04:06 |
| Last Modified: | 28 Aug 2018 05:51 |
| URI: | http://ir.cftri.res.in/id/eprint/10776 |
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