Modelling solubility of phenolics of mango ginger extract in supercritical carbon dioxide using equation of state and empirical models.

Solubility of phenolics of mango ginger extract
in supercritical carbon dioxide was studied at 40–
60 °C and 100–350 bar. Critical temperature, critical
pressure and critical volume of caffeic acid, the principal
component of the extract were calculated using
group contribution methods and compared with the
values obtained by CHEMDRAW®. Vapor pressure of
caffeic acid was predicted by Reidel method. Solubility
prediction in supercritical carbon dioxide was studied
using two different equation of states (EOS) models
and eight empirical models. Peng-Robinson EOS predicted
the solubility very well with average deviation of
0.68 % from the experimental solubility. Empirical
equations based on the simple error minimization using
non-linear regression method which do not require complex
physiochemical properties was also found suitable
to predict the solubility at different extraction conditions.
Jouyban et al. model showed very less deviation
(2.25 %) for predicted solubility values from the
experiment.