Sugasini, D. and Lokesh, B. R. (2013) Rats fed linseed oil in microemulsion forms enriches the cardiac sarcoplasmic reticulum lipids with docosahexaenoic acid and lower calcium transport. Journal of Functional Foods. 1863 -1872.
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Abstract
The effect of feeding rats with whey protein or lipoid microemulsion of n-3 rich linseed oil
(LSO), and n-6 rich sunflower oil (SNO) compared to native or microemulsion forms of each
oil for 60 days on fatty acid composition, Ca2+Mg2+ ATPase, Ca2+ uptake and membrane fluidity
of rat cardiac sarcoplasmic reticulum (SR) were assessed. Rats consuming LSO in
lipoid microemulsion showed higher levels of ALA (18:3, n-3) conversion to DHA (22:6,
n-3) when compared to rats given LSO in native form. Compared to all other dietary treatments,
the alterations in the n-6/n-3 PUFA composition of SR of rats given LSO in lipoid
microemulsion effected the greatest changes in Ca2+Mg2+ ATPase activity and Ca2+ uptake
which effectively reduced Ca2+ transport. Therefore, the LSO in lipoid microemulsion
confers similar heart healthy fatty acid compositional and calcium transport changes
and potentially anti-arrhythmic effects similar to fish oils.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Alpha linolenic acid Docosahexaenoic acid Microemulsions Sarcoplasmic reticulum Ca2+Mg2+ ATPase Ca2+ transport |
| Subjects: | 500 Natural Sciences and Mathematics > 07 Life Sciences > 03 Biochemistry & Molecular Biology > 11 Lipid Biochemistry 600 Technology > 08 Food technology > 19 Lipids-oils/fats > 01 Oilseeds |
| Divisions: | Lipid Science and Traditional Foods |
| Depositing User: | Food Sci. & Technol. Information Services |
| Date Deposited: | 22 Sep 2016 10:28 |
| Last Modified: | 22 Sep 2016 10:28 |
| URI: | http://ir.cftri.res.in/id/eprint/12304 |
