Hypolipidaemic and antioxidant effects of functional cereal-mix produced with probiotic yeast in rats fed high cholesterol diet

The effects of cereal-mix fermented with probiotic Pichia kudriavzevii OG32 on plasma antioxidant
markers and serum and hepatic lipids in rats fed with high cholesterol diet were
investigated. The groups fed on high cholesterol diet supplemented with probiotic cerealmix
had significantly higher levels of plasma antioxidant activity (trolox equivalent) and
lower levels of serum total cholesterol, triacylglycerol and low density lipoproteincholesterol
(LDL-C), when compared with the group fed high cholesterol diet without
supplementation. Atherogenic index decreased from 1.94 ± 0.05 in positive control group to
0.66 ± 0.01 in HCD+10% CBFF fed group. High-cholesterol diet significantly increased the hepatic
total cholesterol and triacylglycerol when compared to the negative control group, but the
supplementation of the high cholesterol diet with different proportions of the fermented
cereal-mix lowered the hepatic total cholesterol and triacylglycerol.