Xanthine scaffold: scope and potential in drug development.

Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.Medicinal plants have been the basis for discovery of various important marketed
drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine,
theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
giving them popular recognition. These compounds are best known for their
diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase
inhibition, antagonization of adenosine receptor, anti-inflammatory, antimicrobial,
anti-oxidant and anti-tumor activities. These properties incentivize to
use xanthine as scaffold to develop new derivatives. Chemical synthesis
contributes greater diversity in xanthine based derivatisation. With highlighting
the existing challenges in chemical synthesis, the present review focuses the
probable solution to fill existing lacuna. The review summarizes the available
knowledge of xanthine based drugs development along with exploring new
xanthine led chemical synthesis path for bringing diversification in xanthine
based research. The main objective of this review is to explore the immense
potential of xanthine as scaffold in drug development.