Ionic liquid-based microwave-assisted extraction of Heneicos-1-ene from coriander foliage and optimizing yield parameters by response surface methodology.

In this study, an efficient ionic liquid (IL)-based microwave-assisted extraction (IL-MAE) was
employed for the extraction of Heneicos-1-ene from coriander foliage. Quantification of Heneicos1-ene was carried out using high-performance liquid chromatography. Parameters affecting extraction such as material to solvent ratio (1:10, 1:15, and 1:20), types of IL ([CH3(CH2)3]4NF,
[BMIM][PF6], [BMIM][BF4], and [C6H5]4P[Br]), concentration of IL (0.1, 0.5, and 1.0 M), microwave
power (200, 500, and 800 W), extraction temperature (50, 70, and 90 �C) and extraction time (2, 6,
and 10 min) were evaluated. Response surface methodology was applied to determine the optimum levels of these parameters to get maximum yield. The optimal conditions were achieved at
800 W, 90 �C for 2 min at a material to solvent ratio of 1:10 using 0.1 M solution of [BMIM][BF4], to
get maximum predicted yield of Heneicos-1-ene (412.8 mg/100 g) as against 408.5 ± 1.14 mg/100 g
for experimental value with 0.991 correlation coefficient. IL-MAE resulted in 5.85 times higher yield
as compared to the conventional method (69.77 ± 1.8 mg/100 g).