Sleep and Gonadotrophin Hormones.

Sleep plays a key role in neuroendocrine functioning and glucose metabolism. Currently existing data reveal that restriction of sleep duration
results in adverse health effects. Sleep plays an imperative role in endocrine systems. Sleep causes the episodic secretion of gonadotrophin
through modulation of neurotransmitters activity. Research on the significance of sex and gonadotrophic hormone in causing sleep disparities
and its effects on cognition among men and women is gaining increased awareness. Epidemiologic, preclinical, and clinical studies have
reported that sleep deprivation causes alteration of metabolic endocrine functions, including reduced glucose tolerance, insulin sensitivity, and
leptin levels with increased cortisol and ghrelin levels. Men with lesser levels of testosterone and women with elevated levels of progesterone
are more susceptible to the effects of sleep restriction on cognition and emotion processing tasks. The present integrative review highlights the
effects of sleep deprivation on sex and gonadotrophin hormones and its link to cognitive function.