Functional foods for the management of non-Alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is increasingly evolving and a critical
public health concern, raising the likelihood of liver cirrhosis, type 2 diabetes and
cardiac problems. Existing epidemics of obesity and sedentary life style have lead
to NAFLD’s elevated prevalence. In recent years there is profound change in the
diet pattern, particularly the hypercaloric fat and carbohydrates for preventing or
treating chronic liver disorders such as NASH and NAFLD. Functional and nutri-
tional foods have contributed significantly to NAFLDimprovement and manage-
ment. The justification for exploring functional foods as anti-NAFLD candidates
for the chronic liver disease prevention is derived knowledge from in vitro and in
vivo models. The findings from the in vitro and in vivo studies confirmed that these
compounds are healthy, efficient, reversible inhibitors, when sufficiently consumed
over a lifetime without severe toxicity, suitable for clinical trials and potentially
becoming low-cost medication.