Stabilization of silver nanoparticles within capsaicin encapsulated metalorganic framework material derived from γ-cyclodextrin

Gangothri, M. Venkataswamy and Nanishankar, V. Harohally (2024) Stabilization of silver nanoparticles within capsaicin encapsulated metalorganic framework material derived from γ-cyclodextrin. Journal of Crystal Growth, 648. pp. 1-6.

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Abstract

Capsaicin, a pungent molecule from red chilli is known for its therapeutic benefits. We envisaged, encapsulation of capsaicin in biocompatible MOF materials derived from γ-cyclodextrin (γ-CD) to overcome solubility and pungency attributes. We accomplished Caps@γ-CDMOF, a capsaicin entrapped CDMOF via in situ addition of capsaicin to the synthesis solution of γ-CD CD MOF and subsequently thoroughly characterized employing PXRD, IR, SEM and NMR techniques. We further accomplished deposition of silver nanoparticles (AgNp) inside the MOF crystals of Caps@γ-CDMOF, which was facilitated by its crystallinity. The AgNp deposition was performed via procedure of reaction–diffusion. This is a first example of CDMOF crystals having an encapsulated drug molecule along with silver nanoparticles distributed across the core of the crystal.

Item Type:	Article
Uncontrolled Keywords:	Encapsulation, Capsaicin, Cyclodextrin, MOF, Silver nanoparticle
Subjects:	500 Natural Sciences and Mathematics > 07 Life Sciences > 03 Biochemistry & Molecular Biology > 18 Phytochemistry 600 Technology > 08 Food technology > 30 Spices/Condiments
Divisions:	Plantation Products Spices and Flavour Technology
Depositing User:	Somashekar K S
Date Deposited:	09 Dec 2025 05:24
Last Modified:	09 Dec 2025 05:24
URI:	http://ir.cftri.res.in/id/eprint/20159

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