Gnanesh Kumar, B. S. and Lijina, P. and Akshata, S. H. (2022) N-glycoprofiling of lactoferrin with site-specificity from buffalo colostrum. International Dairy Journal, 127. pp. 1-5.
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Abstract
Lactoferrin (Lf) from buffalo colostrum was probed for N-glycan diversity and abundances that were
previously unknown. Out of four N-glycosylation sites present, two sites, N233NT and N545DT, exhibited
predominantly high-mannose glycans. Site N281 KS showed mainly sialylated hybrid types. A higher
abundance of differentially sialylated hybrid glycans was present at N476QT. In addition, the genetic
variant of Lf was identified. Overall, this study showed that high mannose and hybrid types are the major
glycans in Lf from buffalo colostrum.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | N-glycoprofiling, lactoferrin, buffalo colostrum |
| Subjects: | 500 Natural Sciences and Mathematics > 07 Life Sciences > 03 Biochemistry & Molecular Biology 600 Technology > 08 Food technology > 27 Dairy products |
| Divisions: | Dept. of Biochemistry |
| Depositing User: | Somashekar K S |
| Date Deposited: | 19 Dec 2025 04:37 |
| Last Modified: | 19 Dec 2025 04:37 |
| URI: | http://ir.cftri.res.in/id/eprint/20203 |
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