Effects of aluminium salts on synaptosomal enzymes--an in vitro kinetic study.

Rao, K. S. (1990) Effects of aluminium salts on synaptosomal enzymes--an in vitro kinetic study. Biochemistry international, 22 (4). pp. 725-34. ISSN 0158-5231

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Abstract

Synaptosomal key enzymes, ATPase (Na(+)-K+, Mg2+ and Ca2+ dependent) and AchE, were used as probes to compute IC50-values in order to study neurochemical effects of aluminium salts. Such effects were examined by means of the Toxicity Test Value (TTV), Maximum Chemical Acceptability Value (MCAV) and Omega (omega) value which indicated salt specific toxicity. Kinetics of Ca2(+)-ATPase inhibition by AlF3 was found to be non-competitive.

Item Type:	Article
Uncontrolled Keywords:	synaptosomes, enzymes, aluminium salts
Subjects:	600 Technology > 08 Food technology > 16 Nutritive value > 05 Enzymes
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	12 Nov 2021 10:26
Last Modified:	12 Nov 2021 10:26
URI:	http://ir.cftri.res.in/id/eprint/2341

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