Behaviour of Aspergillus flavus in presence of Aspergillus niger during biosynthesis of aflatoxin B1.

Aspergillus niger or Aspergillus tamarii when grown as mixed cultures with toxigenic A. flavus inhibits
biosynthesis of ariatoxin by A. flavus, owing primarily to its ability to produce inhibitors of aflatoxin
biosynthesis and to their ability to degrade aflatoxin. Gluconic acid partly prevents aflatoxin production. The
other factors such as changes in pH of the medium and the effect on the growth ofA. flavus have no role in
imparting capabilities to these cultures to inhibit aflatoxin production by A. flavus.