Solid substrate mediated changes in ergot alkaloid spectra in solid state fermentation system.

Use of different solid substrates resulted in minor alterations in total alkaloid
production by Clmiceps purpurea 1029c in solid state fermentation system but the changes in
the spectra of ergot alkaloids were of significantly higher magnitudes. Ergonovine accounted for
93% of the total alkaloid production in wheat grain medium while lysergic acid derivatives and
ergonovine comprised of 66% and 32% of total alkaloids in rye grain medium. In contrast,
ergonovine, ergotamine, and lysergic acid derivatives were 35, 35, and 25% respectively of the
total alkaloids with the use of sugar cane pith bagasse impregnated with sucrose. No information
on these aspects was available earlier.