The relationship of dietary B vitamins and proteins to regeneration of tissue constituents in the protein depleted rat.

Wagle, D. S. and Sreenivasan, A. (1960) The relationship of dietary B vitamins and proteins to regeneration of tissue constituents in the protein depleted rat. Proceedings of the symposium on Proteins, Mysore, August. pp. 154-166.

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Abstract

It has been reported that in protein-fasted adult rats, the level of intake of B vitamins may influence protein utilization from diets with uneven distribution of protein and caloric moieties or with intermittent changing levels of protein1 as well as from single or mixed protein diets2. Work from this laboratory has also indicated the beneficial effect of B vitamins in the utilization of low quality protein dietaries. The present report relates to observations on the changes in certain liver and plasma constituents resulting from protein starvation in young adult rats and on the influence of dietary levels of certain B-vitamins (thiamine, riboflavine, niacin, pantothenic acid, pyridoxine, folic acid and vitamin B12) on the rate of regeneration during protein realimentation. The effects of protein quality and quantity as well as specifically of dietary folic acid and vitamin B12 have also been examined in relation to tissue constituents in protein-fasted and refed rats. A deficiency in dietary nitrogen results in an imbalance in protein stores and is characterized by a shift in the distribution of blood and tissue proteins. The pattern of enzyme systems is altered markedly in the liver and to a lesser degree in other tissues. A shift in metabolism involving all nutrients is associated with a loss in tissue proteins. The protein stores can be regenerated by refeeding of proteins, the rate and extent of such repletion being obviously determined by the quality and quantity of the fed protein as well as other dietary essentials including vitamins and minerals.

Item Type:	Article
Uncontrolled Keywords:	protein utilization, B vitamins, dietary folic acid
Subjects:	600 Technology > 01 Medical sciences > 12 Metabolism 600 Technology > 08 Food technology > 16 Nutritive value > 04 Vitamins
Divisions:	Dept. of Biochemistry
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	06 Jul 2012 05:39
Last Modified:	06 Jul 2012 05:39
URI:	http://ir.cftri.res.in/id/eprint/6083

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