Ultrasound-Assisted Nucleophilic Substitution Reaction of t-Alkyl Halides with Zinc and Titanium Thiocyanate

Ultrasoundpromotes nucleophilic substitution of t-alkyl halides with
ambident thiocyanate nucleophile, in the form of its zinc or titanium
thiocyanate, under mild conditions to afford the corresponding
thiocyanates selectively, in goodto excellent yields. This improved
synthetic methodology affords a facile access to tertiary thiols via the
corresponding thiocyanate intermediates.