Techno-economic analysis of processes for Aspergillus carbonarius polygalacturonase production.

Nakkeeran, E. and Gowthaman, M. K. and Umesh Kumar, S. and Subramanian, R. (2012) Techno-economic analysis of processes for Aspergillus carbonarius polygalacturonase production. Journal of Bioscience and Bioengineering, 113 (5). pp. 634-640.

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Abstract

A techno-economic analysis of submerged (SmF) and solid state fermentation (SSF) processes for Aspergillus carbonarius polygalacturonase production was performed to make an appropriate process selection. The downstream processing involved integrated membrane process (IMP) and alginate affinity precipitation (AAP). For a production scale of 30 kL purified polygalacturonase concentrate per year, the total upstream cost of SmF was 14% lower than the SSF process. Downstream processing cost by IMP was 47% lower than AAP. The SmF-IMP process required a total capital investment that was 15–24% lower than the SmF-AAP and SSF-AAP processes. The corresponding unitary product cost was also lower by 24–36% in SmFIMP process. Thus the SmF-IMP process proved to be very attractive from an economic point of view.

Item Type:	Article
Uncontrolled Keywords:	Economic analysis; Aspergillus carbonarius; Polygalacturonase; Submerged fermentation; Solid-state fermentation; Integrated membrane process; Alginate affinity precipitation
Subjects:	500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 16 Enzyme Chemistry 500 Natural Sciences and Mathematics > 07 Life Sciences > 04 Microbiology > 04 Fungi
Divisions:	Food Engineering Food Microbiology
Depositing User:	Food Sci. & Technol. Information Services
Date Deposited:	25 Apr 2012 06:55
Last Modified:	30 May 2012 11:07
URI:	http://ir.cftri.res.in/id/eprint/10677

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